Biocompatible surfaces for In vivo sensors

This activity is pursuing the use of MEMS as sensors for the continuous monitoring of physiological parameters in the human body. Such in vivo sensors are now being used during surgery or for a short period after surgery. However, the use of these sensors for permanent or long-term implantation in the human body raises the issue of biocompatibility, the body´s reaction to the implanted sensor as well as the sensor´s reaction to the body. The group has developed a sensor that can be used for measurement of e.g. intracranial pressures in people suffering from hydrocephalus and is looking at key challenges for such a sensor when implanted in the human body. These includes corrosion and the accumulation of proteins, cells and other biological material on the sensor surface, the creation and designs of protective films for sensors and the effects of protective films on sensor sensitivity.

Ingelin Clausen